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	<title>GlycosBio</title>
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		<title>Glycos Biotechnologies Granted BioNexus Status in Malaysia</title>
		<link>http://www.glycosbio.com/glycos-biotechnologies-granted-bionexus-status-in-malaysia/</link>
		<comments>http://www.glycosbio.com/glycos-biotechnologies-granted-bionexus-status-in-malaysia/#comments</comments>
		<pubDate>Thu, 24 Feb 2011 16:05:59 +0000</pubDate>
		<dc:creator>richard</dc:creator>
				<category><![CDATA[News]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=965</guid>
		<description><![CDATA[The Malaysian government has granted Glycos Biotechnologies Inc.  BioNexus Status via the Biotechnology Corp. (BiotechCorp), a national  agency established by the government to support the development of a  Malaysian biotechnology industry. According to GlycosBio, the  announcement marks a key milestone in its expansion into Malaysia, where  the company is constructing [...]]]></description>
			<content:encoded><![CDATA[<p>The Malaysian government has granted Glycos Biotechnologies Inc.  BioNexus Status via the Biotechnology Corp. (BiotechCorp), a national  agency established by the government to support the development of a  Malaysian biotechnology industry. According to GlycosBio, the  announcement marks a key milestone in its expansion into Malaysia, where  the company is constructing a biorefinery and R&amp;D facility in  Bio-XCell, a biotechnology park.</p>
<p>BioNexus Status is a recognition awarded by the Malaysian government  to qualified companies that participate in and undertake value-added  biotechnology activities. To date, 187 companies, 10 with U.S.  shareholding, have been granted BioNexus Status.</p>
<p>According to GlycosBio CEO Richard Cilento, there are several  requirements companies have to meet in order to gain the status. “You  have to be a provider of services or products based on either life  sciences or industries that substantially utilize biotechnology  processes,” he said. Qualified companies also have to make a commitment  to research and development activities and ensure a significant percent  of its employees are “knowledge workers,” as opposed to laborers.  Selected companies are also required to commit to comply with all  applicable laws, regulations and guidelines. They must also establish a  separate legal entity based in Malaysia.</p>
<p>The financial benefits of BioNexus Status are impressive, Cilento  said. While the government of Malaysia typically maintains a portion of  ownership, up to 30 percent, in companies located within the nation,  those with BioNexus Status are given a commitment to have freedom of  ownership, he said. This means that GlycosBio is able to maintain 100  percent ownership of its Malaysian projects. In many instances, the  government may also limit from where a company can secure funds,  customarily requiring that working capital dollars are sourced within  Malaysia. However, BioNexus Status companies are given the freedom to  source funds globally, Cilento said.</p>
<p>BioNexus Status companies also receive important tax benefits. For a  period of time, Cilento said they are given tax exemptions on profits  and distributed dividends. “In certain cases, exemptions [are also made]  on import duties and sales tax for raw materials and machinery,” he  continued. “The concept of exemption of import duties and sales tax is  quite significant.” In some instances, Cilento said BioNexus Status  companies are also allowed to take double deductions on expenditures  incurred on research and development activities.</p>
<p>“We are honored that BiotechCorp has granted GlycosBio with the  esteemed designation of BioNexus Status and proud to join this elite  group of companies,” said Cilento. “The BioNexus Status demonstrates the  benefits of a collaborative effort between private enterprises and the  strategic objectives of the Malaysian government. Having the support of  BiotechCorp and working closely with their dedicated professionals has  proven to be a key differentiator for GlycosBio and the emerging  biochemical value chain we are supporting.”</p>
<p>By Erin Voegele</p>
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		<title>Going Global</title>
		<link>http://www.glycosbio.com/going-global/</link>
		<comments>http://www.glycosbio.com/going-global/#comments</comments>
		<pubDate>Thu, 24 Feb 2011 15:59:58 +0000</pubDate>
		<dc:creator>richard</dc:creator>
				<category><![CDATA[News]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=961</guid>
		<description><![CDATA[As President Obama emphasized in his State of the Union address,  America features the world’s greatest innovation machine. This is  clearly demonstrated by the sheer volume of biochemical startups our  nation has produced in recent years.
While America leads in innovation and technology development, scaling  up those processes overseas is often an [...]]]></description>
			<content:encoded><![CDATA[<p>As President Obama emphasized in his State of the Union address,  America features the world’s greatest innovation machine. This is  clearly demonstrated by the sheer volume of biochemical startups our  nation has produced in recent years.</p>
<p>While America leads in innovation and technology development, scaling  up those processes overseas is often an attractive option for domestic  companies. There are many reasons for this, including a lack of  incentives in the U.S., lower construction and operational costs,  greater feedstock availability and access to downstream markets.</p>
<p>It is important for these companies to understand that no matter  where they choose to site projects—whether in North America, Southeast  Asia or Brazil—they will encounter different sets of benefits and  challenges. Each region is unique. Local customs, political  environments, laws, regulations and resources all need to be addressed  in order to develop a successful project. For many companies, the  formation of local partnerships seems to be the most advantageous way to  navigate the complexities of these markets.</p>
<p>Each biorefining company is unique, and each has its own set of  factors to consider when siting a project. BioAmber Inc. is currently  finalizing the site for a North American plant and is in discussions  with a consortium to construct another in Southeast Asia. “These are  firm projects that are underway,” says J.F. Huc, BioAmber’s president  and CEO, noting that his company is also exploring the possibility of  building a plant in South America.</p>
<p>According to Huc, BioAmber looks at four primary factors when  scouting locations for a plant. First is the cost to serve customers.  This includes feedstock, utility and final shipping costs. “Tied closely  to the supply chain is feedstock availability,” he says. “The more  abundant the supply of feedstock, or the variety of feedstocks  available, the more likely you are to manage the cost of your raw  materials. In places like Thailand, being able to switch from sugarcane  to tapioca gives you a hedge against a sharp spike in one or the other.”</p>
<p>“The second very important consideration for us is local partners,”  Huc says, adding that he believes it is necessary to find local partners  who can access the best labor pools and subcontractors, oversee the  engineering and construction of the plant, operate the plant effectively  and contribute to feedstock security. “That is particularly important  in places like Brazil, where you have large, integrated sugarcane  producers.”</p>
<p>Third is government support for nondilutive funding. This doesn’t  necessarily mean access to grants, but includes the availability of  financing mechanisms like low-interest loans and loan guarantees to help  defray the cost of capital, Huc says.</p>
<p>The final consideration for BioAmber is what Huc calls the  specificities of the site. This includes proximity of infrastructure,  including electrical service, truck weighing stations, rail spurs, and  waste water management systems. “These are all things that often will be  pre-existing on a site and can significantly reduce your initial  capital expense,” he says.</p>
<p>NatureWorks LLC has its own unique set of considerations, and is  actively vetting sites for additional production capacity. Market demand  for the company’s Ingeo bioplastic has been growing by approximately 25  to 30 percent a year, says Steve Davies, NatureWorks’ director of  marketing and public affairs. Current projections indicate that the  entire capacity of the company’s Nebraska plant will be sold within the  next three years, making it necessary to construct additional capacity  to meet demand. A new location will have to be chosen for this capacity  by midyear in order for the additional capacity to be brought online in  the 2014-‘15 timeframe. NatureWorks is currently exploring options in  both North America and Southeast Asia. While Davies stresses that  additional production is highly likely to be installed in both regions  in the future, the decision where the first expansion takes place is  expected to be based, in part, on locally available incentives.</p>
<p>NatureWorks looks at three primary factors when considering locations  for a plant, Davies says. No. 1 is the availability of feedstock—not  just feedstock currently employed by its process, but also the  availability of lignocellulosic feedstock for future use. “The second is  the extent to which an end market exists in a region,” he continues.  “Third is, of course, regional incentives, what’s being offered and how  interested is that country or region in getting into the biochemicals  business.” A variety of secondary factors also considered includes  energy costs, logistics, workforce availability, trade structure, and  import and export duties.</p>
<p><strong>Partnering for Success</strong></p>
<p>Once a location is chosen for a new plant, most biorefining companies  seem to be making it a priority to find reliable local partners. Glycos  Biotechnologies Inc. is in the process of developing a plant in  Malaysia. In fact, the company had a team on the ground in January  working to hire a construction partner.</p>
<p>Malaysia is a very friendly environment to develop this type of  project, says GlycosBio CEO Richard Cilento. “The government really has a  long-term business plan—or strategy—to bring in new technologies and  new industries into the country.” GlycosBio has formed a partnership  with two government corporations, the Malaysian Biotechnology Corp. and  Bio-XCell, to help expedite development of its plant. While these  corporations will not have any ownership in the project, Cilento notes  they have been invaluable in helping the project succeed.</p>
<p>These government corporations have formed an industrial biotechnology  park where they have plots and utilities in place for companies like  GlycosBio. The entities also serve as a resource that supports hiring  needs and the formation of off-take and feedstock supply agreements. “It  would be like finding a needle in a haystack to really try to  understand the local market and [identify] the right essential partners  on the operational execution side,” Cilento says. “This [partnership] is  a tremendous benefit. It would be very difficult to do this without  such a partner.” The partnership also helps to instill local confidence  in the project. “The biochemical market is still in the early stages, so  you’re trying to demonstrate a technology that is really cutting edge,”  Cilento continues. “A partner like that gives the market confidence.  They provide a lot of credibility.”</p>
<p>Alternatively, Myriant Technologies Inc. is pursuing an overseas  project via an agreement to develop a joint venture that was signed with  the PTT Chemical Group of Thailand. “To try to develop a project from  half a world away is enormously costly and time consuming,” says Sam  McConnell, Myriant’s senior vice president for corporate development.  “It’s hard enough to do here in the U.S., but to serve markets in Asia  we sat down and decided we really need a local partner who understands  how to get things done and has the necessary resources.”</p>
<p>Even before the agreement with PTT Chemical was signed, McConnell  says Myriant was already looking to develop a project in Southeast Asia,  largely because of the incentives that are available. “A number of  countries, including Thailand, have been pretty aggressive in looking to  attract high-tech manufacturing, so the fact that PTT Chemical is in  one of those countries was certainly another big plus,” he says.</p>
<p>NatureWorks’ strategy in the Southeast Asian marketplace could vary  from establishing a local partnership with locally based companies, to  simply establishing a local presence itself, says Davies. “We’ve already  done that on the sales and marketing end,” he continues. “We have local  sales and marketing teams based in China, Hong Kong, Japan and Korea.”  Those locally sourced teams are great at addressing challenges  associated with language, customs and logistics, Davies says.</p>
<p>When selecting local partners for a project, Huc notes that you want  to target partners who have a track record of building and operating  similar facilities, such as ethanol or chemical plants. “When I say good  track record, I mean they haven’t run into problems from an  environmental or permitting standpoint, or security. They haven’t had a  lot of accidents onsite—the companies that build projects on-time and  on-budget and have privileged relationships with local trades and  subcontractors.”</p>
<p><strong>IP Protection</strong></p>
<p>One area of particular concern for many companies is the protection  of intellectual property (IP). Anytime you build and operate a plant,  you are going to develop a lot of know-how that you are not necessarily  going to patent, notes Huc.</p>
<p>When you bring technology into a new area, intellectual property of  all kinds can be very difficult to manage. “You can have IP leakage  during the planning and engineering stage, you can have IP leakage  during the operation phase,” Huc notes. “In our experience, the best way  to manage that type of IP leakage is to have strong, local partners who  have a degree of influence on the authorities that are responsible for  IP protection, and have some dissuasive influence on individuals.”</p>
<p>“I think [IP theft] is something that has happened quite extensively  in China, but you are also vulnerable to it in other Asian countries,”  Huc says. “The real risk is that you have somebody who appropriates your  process know-how and replicates what you are doing right down the  street. Most countries will claim to have preventative laws now. The  problem is when something like that happens, despite having laws in  place, you often find yourself having very little recourse, particularly  in countries that have large domestic markets for your product. You  have recourse if they infringe on your intellectual property and then  export it into a market like the U.S., where you do have strong laws and  precedence, but if you are in a country like China or South Korea,  where there is a large local market, it’s very difficult for you to stop  them from selling it domestically, especially if they are not dealing  with foreign currency.”</p>
<p>However, Cilento notes that, in some regions, IP protection isn’t  really a challenge. Rather, it is something that companies need to be  aware of and manage from the beginning. “Many of the countries in  Southeast Asia were born from U.K. law as colonies of the U.K. years and  years ago,” he says. These countries understand that people question  the security of IP in their region. “They go out of their way to  differentiate themselves from different parts of the world where IP  control and theft are more prevalent. Certainly in Malaysia and  Singapore, they really try to put their best foot forward to give us  some comfort.”</p>
<p><strong>Managing Logistics</strong></p>
<p>Another primary challenge when developing a project overseas is the  need to be able to manage that project from half a world away. In other  words, a company’s physical presence can be difficult to manage. “For  new technologies, the commissioning and ramp-up of the plant are very,  very important,” Huc says. “That expertise tends to reside within the  company that is deploying the technology. The further you are from your  headquarters and where your engineers are, the more difficult it is to  oversee that. To manage that complexity, you have to send people abroad  for long periods of time.”</p>
<p>The time difference is certainly a challenge as well, notes Cilento.  “You are looking at a 10- to 13-hour time difference,” he says. “Travel  to and from is easily a two or three day process, that’s without  recovery time after you get back. You have to really invest a lot of  time and energy in travel. You need to be able to take advantage of  technologies like video conferencing and other techniques to minimize  these challenges. Hiring both labor-level and senior management level  employees is something that is not insurmountable, but without any  critical mass or resources in country, you are really starting from  scratch.”</p>
<p>That said, Cilento notes that GlycosBio is not anticipating any  problems finding qualified employees. Malaysia features a large  petrochemical industry and has also been very active in medical  biotechnology. Assimilating those skills and professionals to industrial  biotechnology shouldn’t be that difficult, he says. However, Cilento  also notes that it is important to take time during local visits to meet  with the local people and begin the recruiting process very early on in  a project’s development.</p>
<p>As biorefining companies continue to expand and establish new  production facilities around the world, certain challenges will be  diminished, while others will remain. With each plant a company builds,  the deployment of the technology itself will become more streamlined,  says Huc. This is because after a company builds and operates a few  plants, it will have gained knowledge to enable the design of more  robust engineering packages. However, the establishment of each new  location around the globe will still be complex in terms of finding the  right partners and scaling up in a new cultural environment.</p>
<p>Author: Erin Voegele<br />
Associate Editor, <em>Biorefining Magazine</em></p>
]]></content:encoded>
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		<title>Glycos Biotechnologies Awarded BioNexus Status from the Malaysian Biotechnology Corporation</title>
		<link>http://www.glycosbio.com/glycos-biotechnologies-awarded-bionexus-status-from-the-malaysian-biotechnology-corporation/</link>
		<comments>http://www.glycosbio.com/glycos-biotechnologies-awarded-bionexus-status-from-the-malaysian-biotechnology-corporation/#comments</comments>
		<pubDate>Tue, 22 Feb 2011 06:24:02 +0000</pubDate>
		<dc:creator>client</dc:creator>
				<category><![CDATA[Press Releases]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=951</guid>
		<description><![CDATA[Government Recognition Delivers Competitive Advantage for Biochemical Company’s Expansion and Commercialization in Malaysia
 
HOUSTON, TX – February 22, 2011 – Glycos Biotechnologies, Inc. (GlycosBio), an international biochemical company commercializing advanced biological processes that convert low-value feedstocks into high-value sustainable chemicals, today announced it has been granted the BioNexus Status from the Malaysian Government via Biotechnology [...]]]></description>
			<content:encoded><![CDATA[<p align="center"><em>Government Recognition Delivers Competitive Advantage for Biochemical Company’s Expansion and Commercialization in Malaysia</em></p>
<p><strong> </strong></p>
<p><strong>HOUSTON, TX – February 22, 2011</strong> – Glycos Biotechnologies, Inc. (GlycosBio), an international biochemical company commercializing advanced biological processes that convert low-value feedstocks into high-value sustainable chemicals, today announced it has been granted the BioNexus Status from the Malaysian Government via Biotechnology Corporation (BiotechCorp), the national agency set up by the Malaysian government for the development of biotechnology in Malaysia.  This announcement marks another key milestone in GlycosBio’s expansion into Malaysia with the construction of the Company’s industrial biochemical plant and biotechnology research and development facility in Bio-XCell, a dedicated biotechnology park in Johor, Malaysia.</p>
<p>BioNexus Status is a recognition awarded by the Malaysian Government, through BiotechCorp, to qualified companies that participate in and undertake value-added biotechnology activities.  To date, 187 companies have been granted the BioNexus status and ten of these companies have United States shareholding.</p>
<p>“We are honored that BiotechCorp has granted GlycosBio with the esteemed designation of BioNexus Status and proud to join this elite group of companies,” said Richard Cilento, Chief Executive Officer of Glycos Biotechnologies.  “GlycosBio will gain a number of financial incentives and business development support services with this status further excelling our growth and expansion efforts in the Malaysian region.  The BioNexus status demonstrates the benefits of a collaborative effort between private enterprises and the strategic objectives of the Malaysian government. Having the support of BiotechCorp and working closely with their dedicated professionals has proven to be a key differentiator for GlycosBio and the emerging biochemical value chain we are supporting.”</p>
<p>GlycosBio was one of the first biochemical companies to partner with BiotechCorp in 2010 to construct a biochemical plant and biotechnology research and development facility in the Bio-XCell biotechnology ecosystem. Bio-XCell is Malaysia’s dedicated biotechnology park for industrial and healthcare biotechnology.  GlycosBio’s expansion plans are on schedule with the facilities construction and are expected to complete in 2012.  GlycosBio plans to focus much of its initial research and development efforts on creating isoprene to support Malaysia’s rubber industry.</p>
<p>“GlycosBio’s presence in Bio-XCell will not only provide Malaysia with human capital development and expanded investment opportunities but also support several of Malaysia’s economic objectives from providing palm oil and oleochemical producers more sustainable production methods to supporting the isoprene related industry which may include polymers such as rubber,” said Iskandar Mizal Mahmood, Chief Executive Officer, Malaysian Biotechnology Corporation.  “As one of the first companies to participate in the Bio-XCell ecosystem, GlycosBio will be a critical contributor to Malaysia’s near and long-term industrial and biotechnology goals.”</p>
<p>BioNexus Status companies enjoy a set of incentives contained within the BioNexus Bill of Guarantees.  BioNexus Status companies also receive continuous support and assistance from BiotechCorp on immigration related matters, IP advisory and regulatory services and employment related matters.  BiotechCorp also provides a wide range of capacity building programs covering a variety of subject matter to assist biotechnology entrepreneurs in managing their business locally and internationally.</p>
<p><strong>About Glycos Biotechnologies, Inc.</strong></p>
<p>Glycos Biotechnologies, Inc. (“GlycosBio”) is an international biochemical company commercializing advanced metabolic engineering and microbial strain processes that convert multiple low value feedstocks into a range of high value sustainable chemicals. By designing a portfolio of differentiated microorganisms, GlycosBio’s bioconversion technology produces a diverse set of chemicals, including substitutes for fossil fuel derived petrochemicals, meeting the growing global demand for clean, environmentally safe biochemicals.</p>
<p>GlycosBio is privately held and focused on biochemical commercialization and production with established global partnerships including relationships with petrochemical companies to secure low cost, non-petroleum based chemicals.  For more information, visit <a href="../">www.glycosbio.com</a>.</p>
<p><strong>About BiotechCorp</strong></p>
<p>BiotechCorp is the lead development agency for the biotech industry in Malaysia and acts as a central contact point providing support, facilitation, and advisory services for life sciences companies in Malaysia. Since its establishment in 2005, BiotechCorp has played a key role in building the biotech business in Malaysia. To date, BiotechCorp has facilitated the development of 187 BioNexus-status companies in Malaysia, with total approved investment of close to RM 2 billion. BioNexus-status companies are international and Malaysian biotech companies that qualify for fiscal incentives, grants, and guarantees administered by BiotechCorp. For more information, visit <a href="http://www.biotechcorp.com/my">www.biotechcorp.com/my</a>.</p>
<p><strong>About Bio-XCell</strong></p>
<p>Bio-XCell is a biotechnology park and ecosystem for industrial and healthcare biotechnology, with a focus on manufacturing and R&amp;D. Developed by Malaysian Bio-XCell Sdn Bhd, a joint venture company between BiotechCorp and UEM Land, the park is slanted to be the new regional biotech hub of Asia. Capitalising on value propositions of both its shareholders, Bio-XCell provides comprehensive infrastructure, services, incentives and benefits to drive the growth for the biotechnology sector.</p>
<p>Strategically located in Nusajaya, Iskandar Malaysia, the resource-rich state of Johor, Bio-XCell provides global connectivity through the network of five seaports and two international airports, all within 59kms. For information or leasing inquiries, log on to <a href="http://www.bio-xcell.com/">www.bio-xcell.com</a>.</p>
<p><strong>MEDIA CONTACT</strong></p>
<p>Suzanne Tormollen<br />
Atingo Public Relations<br />
281-785-1280<br />
<a href="mailto:suzanne@atingo.com">suzanne@atingo.com</a></p>
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		<title>Glycos Biotechnologies Appoints Gary Mossman to Board of Directors</title>
		<link>http://www.glycosbio.com/glycos-biotechnologies-appoints-gary-mossman-to-board-of-directors/</link>
		<comments>http://www.glycosbio.com/glycos-biotechnologies-appoints-gary-mossman-to-board-of-directors/#comments</comments>
		<pubDate>Thu, 10 Feb 2011 05:50:59 +0000</pubDate>
		<dc:creator>client</dc:creator>
				<category><![CDATA[Press Releases]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=949</guid>
		<description><![CDATA[Specialty Chemicals and Pharmaceutical Industry Veteran Tapped for Business and Multi-National Experience
HOUSTON, TX – February 10, 2011 – Glycos Biotechnologies, Inc. (GlycosBio), an international biochemical company commercializing advanced metabolic engineering and microbial strain processes to convert low-value feedstocks into high-value sustainable chemicals, today announced the appointment of Gary Mossman, chemical industry veteran, to the Company’s [...]]]></description>
			<content:encoded><![CDATA[<p align="center"><em>Specialty Chemicals and Pharmaceutical Industry Veteran Tapped for Business and Multi-National Experience</em></p>
<p><strong>HOUSTON, TX – February 10, 2011</strong> – Glycos Biotechnologies, Inc. (GlycosBio), an international biochemical company commercializing advanced metabolic engineering and microbial strain processes to convert low-value feedstocks into high-value sustainable chemicals, today announced the appointment of Gary Mossman, chemical industry veteran, to the Company’s Board of Directors.  Mossman’s experience spans both large and small molecular technology with more than 40 years of executive management and investment responsibility in private and public pharmaceutical and specialty chemical firms.</p>
<p>“GlycosBio is very pleased to welcome Gary to our Board of Directors,” said Richard Cilento, Chief Executive Officer of Glycos Biotechnologies.  “Gary’s range of expertise in chemicals, pharmaceuticals and manufacturing coupled with his business, technical and leadership background will play an integral role in GlycosBio’s efforts to continue developing innovative products and further advance the Company’s position as a leader in producing sustainable biochemicals.”</p>
<p>Mossman is currently Chief Operating Officer (COO) and Director of PLx Pharma, an emerging Pharma company and Chairman of Redline Industries, a metal fabricator.  In addition, he is a director of the Nassau Bay Economical Development Council and the CCISD Educational Foundation.   Previously, Mossman held the position of Executive Vice President and COO of Cambrex Corporation where he was responsible for global operations of this leading provider of API’s including Generics, Biotech and Pharma Development Services, Drug Delivery, and Diagnostic Products.  Mossman also served as Chief Executive Officer and Vice Chairman of Dixie Chemical Company, a top tier specialty chemical company.</p>
<p>“The majority of my professional career has been focused in specialty chemicals, biotechnology and biopharmaceuticals,” said Mossman. “GlycosBio is a smart company making incredible discoveries to help further the industry’s advancement toward biochemical independence and I’m excited to have the opportunity to extend my experience and knowledge to GlycosBio to help them continue to reach their business goals.”</p>
<p>Mossman joins current GlycosBio Board of Directors members including Walter Burnap, President and Chief Financial Officer of GlycosBio; Richard Cilento, Chief Executive Officer of GlycosBio; Steve Jurvetson, Managing Director, Draper Fisher Jurvetson; and Dan Watkins, Managing Director of DFJ Mercury.</p>
<p><strong>About Glycos Biotechnologies, Inc.</strong></p>
<p>Glycos Biotechnologies, Inc. (“GlycosBio”) is an international biochemical company commercializing advanced metabolic engineering and microbial strain processes that convert multiple low value feedstocks into a range of high value sustainable chemicals. By designing a portfolio of differentiated microorganisms, GlycosBio’s bioconversion technology produces a diverse set of chemicals, including substitutes for fossil fuel derived petrochemicals, meeting the growing global demand for clean, environmentally safe biochemicals.</p>
<p>GlycosBio is privately held and focused on biochemical commercialization and production with established global partnerships including relationships with petrochemical companies to secure low cost, non-petroleum based chemicals.  For more information, visit <a href="../">www.glycosbio.com</a>.</p>
<p><strong>MEDIA CONTACT</strong></p>
<p>Suzanne Tormollen<br />
Atingo Public Relations<br />
281-785-1280<a href="mailto:suzanne@atingo.com"><br />
suzanne@atingo.com</a></p>
]]></content:encoded>
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		<title>Glycos Biotechnologies to Present at the Next Generation Bio-Based Chemicals Summit</title>
		<link>http://www.glycosbio.com/glycos-biotechnologies-to-present-at-the-next-generation-bio-based-chemicals-summit/</link>
		<comments>http://www.glycosbio.com/glycos-biotechnologies-to-present-at-the-next-generation-bio-based-chemicals-summit/#comments</comments>
		<pubDate>Tue, 08 Feb 2011 05:10:56 +0000</pubDate>
		<dc:creator>client</dc:creator>
				<category><![CDATA[Press Releases]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=946</guid>
		<description><![CDATA[HOUSTON, TX – February 8, 2011 – Glycos Biotechnologies, Inc. (GlycosBio), an international biochemical company commercializing industrial biological processes to convert low-value feedstocks into high-value sustainable chemicals, today announced the Company will be presenting at the Next Generation Bio-Based Chemicals Summit taking place February 14 – 17th in San Diego, CA.
Paul Campbell, Chief Science Officer [...]]]></description>
			<content:encoded><![CDATA[<p><strong>HOUSTON, TX – February 8, 2011 </strong>– Glycos Biotechnologies, Inc. (GlycosBio), an international biochemical company commercializing industrial biological processes to convert low-value feedstocks into high-value sustainable chemicals, today announced the Company will be presenting at the Next Generation Bio-Based Chemicals Summit taking place February 14 – 17<sup>th</sup> in San Diego, CA.</p>
<p>Paul Campbell, Chief Science Officer for GlycosBio, will participate in a panel with other leading biochemical companies to explore the growing shift in the industry from biofuel to biochemical production.  Panelists will examine why companies may be choosing biochemicals over biofuels, the long-term sustainability and future of such a choice, and the potential synergies between these two strategies.</p>
<p>With more than 90 speakers confirmed, the 2<sup>nd</sup> Annual Next Generation Bio-Based Chemicals Summit is quickly becoming a growing tradition for key industry players, leading developers, government representatives, ground breaking researchers, and renowned financiers to gather, discuss and foster cutting edge innovations for bio-based chemicals.</p>
<p><strong>What:</strong> “Expanding from Fuels to Chemicals”</p>
<p><strong>Who:</strong> <em>Moderator</em></p>
<p style="padding-left: 60px;">John Eustermann, Partner, Stoel Rivers, LLP</p>
<p style="padding-left: 60px;"><em>Panelists</em></p>
<p style="padding-left: 60px;">Alan Berry, Director, Microbial Physiology and HTS, Novozymes, Inc.</p>
<p style="padding-left: 60px;">Doug Cameron, Managing Director, Alberti Advisors, LLC</p>
<p style="padding-left: 60px;">Paul Campbell, PhD., Chief Science Officer, Glycos Biotechnologies</p>
<p style="padding-left: 60px;">Vonnie Estes, Vice President, Corporate Development, Codexis, Inc.</p>
<p style="padding-left: 60px;">Joseph Kocal, Director of Renewable Research, UOP, a Division of Honeywell, Inc.</p>
<p><strong>Where:</strong> Hilton San Diego Resort &amp; Spa</p>
<p><strong>When:</strong> Wednesday, February 16<sup>th</sup>, 10:30am – 11:30am</p>
<p>For more information about the Next Generation Bio-Based Chemicals Summit, visit <a href="http://www.infocastinc.com/index.php/conference/436">http://www.infocastinc.com/index.php/conference/436</a>.</p>
<p><strong>About Glycos Biotechnologies, Inc.</strong></p>
<p>Glycos Biotechnologies, Inc. (“GlycosBio”) is an international biochemical company commercializing advanced metabolic engineering and microbial strain processes that convert multiple low value feedstocks into a range of high value sustainable chemicals. By designing a portfolio of differentiated microorganisms, GlycosBio’s bioconversion technology produces a diverse set of chemicals, including substitutes for fossil fuel derived petrochemicals, meeting the growing global demand for clean, environmentally safe biochemicals.</p>
<p>GlycosBio is privately held and focused on biochemical commercialization and production with established global partnerships including relationships with petrochemical companies to secure low cost, non-petroleum based chemicals.  For more information, visit <a href="../">www.glycosbio.com</a>.</p>
<p><strong>MEDIA CONTACT</strong></p>
<p>Suzanne Tormollen<br />
Atingo Public Relations<br />
281-785-1280<a href="mailto:suzanne@atingo.com"><br />
suzanne@atingo.com</a></p>
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		<title>Houston Biostartups Strong in Innovation</title>
		<link>http://www.glycosbio.com/houston-biostartups-strong-in-innovation/</link>
		<comments>http://www.glycosbio.com/houston-biostartups-strong-in-innovation/#comments</comments>
		<pubDate>Mon, 24 Jan 2011 16:14:14 +0000</pubDate>
		<dc:creator>richard</dc:creator>
				<category><![CDATA[News]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=973</guid>
		<description><![CDATA[Companies Ride Robust Economic Wave That&#8217;s Been Washing Over the State of Texas
Carol Potera


The recession slowed the economy in  many parts of the United States, but Houston, Texas, boasts a job growth  rate of 11.7%, compared to an average 1.2% nationally, according to Newsweek (November 15, 2010). The city’s 160 life science companies [...]]]></description>
			<content:encoded><![CDATA[<h2>Companies Ride Robust Economic Wave That&#8217;s Been Washing Over the State of Texas</h2>
<p>Carol Potera</p>
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<p>The recession slowed the economy in  many parts of the United States, but Houston, Texas, boasts a job growth  rate of 11.7%, compared to an average 1.2% nationally, according to <em>Newsweek</em> (November 15, 2010). The city’s 160 life science companies account for some of that growth.</p>
<p>Innovations from local medical centers and universities spawn  biotechnology startups. The Texas Medical Center, considered one of the  world’s largest medical complexes, includes the University of Texas  Health Science Center, Baylor College of Medicine, University of  Houston, Texas Heart Institute, and M.D. Anderson Cancer Center. Nearby  Rice University pioneered nanotechnology, and two of its researchers  received the 1996 Nobel Prize in chemistry for discovering  buckminsterfullerenes, the building blocks of nanotechnology.</p>
<p>Fledgling life science companies are aided by the state’s $200  million Texas Emerging Technology Fund, set up to speed innovation and  commercialize research. “The funds help companies cross the valley of  death,” says Deborah Mansfield, director of the life sciences program at  the Houston Technology Center, a nonprofit business accelerator. The  “valley of death” refers to the years after basic research identifies a  promising technology, but the discovery needs validation to attract  venture capital. Numerous examples exist that demonstrate that Houston’s  strong scientific and business climate is helping to advance numerous  startups.</p></div>
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<h3>Better Therapies</h3>
<p>NanoSpectra Biosciences was formed in  2002 to advance the discovery of gold nanoparticles that absorb  near-infrared light and destroy solid tumors. The gold nanoparticles are  sized so that they naturally accumulate in the leaky vasculature of  tumors, but not healthy tissues. The AuroLase® Therapy is infused into  the bloodstream of patients with solid tumors then 12 to 36 hours later,  the tumor is zapped with a near-infrared laser. The gold nanoparticles  convert the light to heat, killing 90% of tumor cells.</p>
<p>AuroLase Therapy “is ideal for tumors that have irregular borders or  are near critical structures,” says Don Payne, president and CEO.  AuroLase is in clinical testing for head-and-neck tumors, and a trial in  prostate cancer will start this year. By targeting only tumor cells in  the prostate, the treatment should eliminate common side effects of  incontinence and erectile dysfunction. Brain and lung cancer also are  prime candidates for AuroLase Therapy, which is reportedly synergistic  with radiation and chemotherapy.</p>
<p>Lone Star Heart  uses proteins and small molecule drugs to stimulate  the repair of damaged heart tissue. Co-founder Robert Schwartz, director  of stem cell engineering at the Texas Heart Institute, discovered that  two proteins act in tandem to convert normal human fibroblasts into  myocytes. “They do it reproducibly over and over by activating cardiac  progenitor cells,” he says.</p>
<p>The proteins are being made recombinantly in bacteria; then they will  be tested for their ability to regenerate damaged heart tissue in pigs.  If successful, the company will file an IND application. Other  co-founders, Eric Olson and Jay Schneider at the University of Texas  Southwestern Medical Center in Dallas, discovered that the drug  isoxasole activates different genes in pericardial cells to promote  tissue growth. The company’s goal is to find new combination therapies  to regenerate human heart cells damaged by heart attacks and other  diseases.</p>
<p>NSAIDs are in the pipeline at PLx Pharma. Rather than discover new  NSAIDs, the company combines the phospholipid lecithin, derived from  soybeans, with over-the-counter aspirin, ibuprofen, and naproxen to  reduce the risk of gastrointestinal toxicity. Lenard Lichtenberger,  Ph.D., professor of integrative biology and pharmacology at the  University of Texas Health Science Center and the company’s CSO, created  the process.</p>
<p>He discovered that phospholipids naturally protect stomach lining  from acid damage, but NSAIDs perturb the natural phospholipid barrier  and allow stomach acid to cause injury.</p>
<p>“Our approach was to find something similar to native phospholipids  that allows aspirin to move through cell membranes easily, yet preserves  the protective barrier,” says Ron Zimmerman, president and CEO.</p>
<p>A study in the November 16, 2010 issue of the <em>American Journal of Gastroenterology</em> showed that in healthy middle-age people taking 325 milligrams of  aspirin daily, PLx’ formulation reduced ulcerative damage to the  gastrointestinal tract by threefold compared to regular aspirin.</p>
<p>Finding ways to complex lecithin to NSAIDs proved surprisingly  challenging, especially for aspirin, which rapidly degrades in the  presence of moisture. Each NSAID requires a unique formulation. The  methods at PLx are more complex than enteric coatings now on the market,  which only push NSAIDs farther down the gastrointestinal tract. The  company plans to carry their NSAID products through the development  stage, then seek commercialization partners.</p></div>
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<h3>Improved Screening Tools</h3>
<p>Risk Assessment Laboratories is  searching for clinical applications for proteomics data. It has  identified five biomarkers for preterm labor. One of the biomarkers is  pre-B-cell colony elongation factor, a master regulator of birth. “We  want to rationally target biomarkers related to a disease,” says Kevin  Rosenblatt, M.D., Ph.D., director of R&amp;D.</p>
<p>Fetal fibronectin is an FDA-approved marker for preterm labor.  However, its positive predictive value is so poor that many  obstetricians do not bother measuring it in cervical fluid. The  biomarker panel identified by Risk Assessment Laboratories requires only  a few microliters of a woman’s peripheral blood. Because the biomarkers  are linked to biological mechanisms of preterm labor, they could lead  to better drugs to prevent or treat preterm labor.</p>
<p>Risk Assessment Laboratories is developing protocols to measure  biomarkers using selective reaction monitoring mass spectrometry. This  reagent-free method detects proteins directly, is highly specific, and  measures multiple markers. “Our goal is to build assays that can be done  in any lab on readily available and easy-to-use mass spectrometers,”  says Dr. Rosenblatt. PerkinElmer, a maker of fetal diagnostic tests, is  funding the preclinical trials.</p></div>
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<p>Nano3D Biosciences sells the  Bio-Assembler™ kit that grows  three-dimensional (3-D) cells in 24 to 48  hours. The cells are first  tagged with magnetic nanoparticles, then  levitated by a magnet field to  grow in three dimensions, as described  in Nature Nanotechnology in April  2010. This method for growing 3-D  cell cultures is faster than  competing products, which take weeks,  according to the company.</p>
<p>Standard tissue culture cells grow in flat two-dimensions, and “gene   expression and signaling are different from that found in vivo,” says   Glauco Souza, Ph.D., CSO. The Bio-Assembler allows co-culturing of   different cell types, and it supports the growth of 25 different cell   lines. Researchers can use the kit for basic research, drug discovery,   toxicity testing, and stem cell and regenerative medicine.</p>
<p>The starter Bio-Assembler kit contains a single microwell and a   device that creates a magnetic field. A six-well plate system is   undergoing beta testing, and a 96-well plate is in development. The   96-well format will support high-throughput screening and allow toxicity   testing in cells that represent in vivo conditions.</p>
<p>In the long-term, the technology could create 3-D tissue for   regenerative medicine. “It all starts with a fundamental building block   of a better representation of living tissue,” says David Lee, president   and CEO.</p></div>
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<p>Today’s researchers have many  exciting new contrast agents to image  biological events within cells,  “but the instrumentation is lagging  behind,” says Robert Kester, Ph.D.,  co-founder and CTO at Rebellion  Photonics. Dr. Kester and colleagues  developed a real-time  hyper-spectral video camera that is compatible  with all standard  microscopes. Called the Arrow™, the camera views  spectral signatures  within cells and decouples them.</p>
<p>Researchers can now track complex biological processes by visualizing   up to 20 different dyes within a single cell. The commonly used   fluoresent proteins, green fluorescent protein (FP), cyan FP, and yellow   FP, all appear green under a microscope because their wavelengths   differ by just a few nanometers.</p>
<p>“Our system decouples multiplexed signals, and you can view them in real time,” says Dr. Kester.</p>
<p>Researchers use the Arrow to understand how neurons fire and change   with age and to find biomarkers for cancer and degenerative and   infectious diseases. Endogenous signals such as autofluorescence can be   isolated and removed to enhance quality. Images are obtained in a  single  snapshot, and the Arrow is more sensitive, faster, less  phototoxic, and  extends the life of cells compared to conventional  scanning microscopy,  according to Dr. Kester.</p>
<p>GlycosBio leveraged technology from Rice University that uses   microorganisms to convert nontraditional carbon sources, such as   glycerol and fatty acids, into higher value chemicals. The company is   focused on producing isoprene, 1,3 propane diol, and ethanol. When   polymerized, isoprene can be turned into latex or automobile tires, and   1,3 propane diol into fibers for carpet or clothing.</p>
<p>The company’s partners in other parts of the world “have lots of   glycerol and want to make it into ethanol to build up a domestic   supply,” says Paul Campbell, Ph.D., CSO. Malaysia’s palm oil industry   produces glycerol as a byproduct, and GlycosBio is setting up a facility   there to ferment it into ethanol.</p>
<p>Closer to home, the company is looking for joint ventures to dispose   of glycerol or fatty acids generated during biodiesel refining. Now   considered waste products that are hauled away, GlycosBio plans to plug   into a plant’s existing infrastructure to cost-effectively convert them   to desirable products.</p></div>
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		<title>Bio-XCell Recognized as Multi-Project Development of the Year</title>
		<link>http://www.glycosbio.com/bio-xcell-recognized-as-multi-project-development-of-the-year/</link>
		<comments>http://www.glycosbio.com/bio-xcell-recognized-as-multi-project-development-of-the-year/#comments</comments>
		<pubDate>Fri, 31 Dec 2010 05:34:09 +0000</pubDate>
		<dc:creator>client</dc:creator>
				<category><![CDATA[News]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=941</guid>
		<description><![CDATA[In Florida, Biofuels Digest announced that Solazyme, Amyris, Neste  Oil, Ceres and Bunge led this years roster of Biofuels Digest Award  winners. The awards, first established in 2008, recognize excellence in  the research, development and commercialization of biofuels, renewable  chemicals and bio-based products. The awards are voted by the Biofuels  [...]]]></description>
			<content:encoded><![CDATA[<p>In Florida, Biofuels Digest announced that Solazyme, Amyris, Neste  Oil, Ceres and Bunge led this years roster of Biofuels Digest Award  winners. The awards, first established in 2008, recognize excellence in  the research, development and commercialization of biofuels, renewable  chemicals and bio-based products. The awards are voted by the Biofuels  Digest editorial board, based on nominations submitted by the Digest’s  readership.</p>
<p>This year’s honoree for <strong>Company of the Year</strong>, went to <strong>Solazyme</strong>.  “Solazyme made the decision several years ago to grow heterotrophic  algae in the dark and harvest renewable oils – and have become the  unquestioned leader in the quest to make an integrated biorefinery  commercially successful in the production of renewable oils for fuels,  foods and other bio-based products,” noted Digest editor Jim Lane.  “Along the ways they’ve racked up an impressive array of partners, and  won contracts to supply biofuels to the US Department of Defense. More  importantly, in every way, they have personified throughout their  organization what it means to be an advanced bio-based company – in the  ways that they have triumphed, and in the ways they have faced  adversity.”</p>
<p>The award for <strong>Product of the Year</strong> (fuels) went to <strong>Amyris</strong> for its farnesane molecule, which it is now producing in Brazil. Made  by adding hydrogen to farnesene (itself produced via Amyris’s novel  modified yeast fermentation technology), it can be utilized as a drop-in  replacement for fossil-based diesel fuels.</p>
<p><strong>Product of the Year</strong> (renewable chemicals) went to <strong>OPX Biotechnology</strong> for its work in reducing the production cost of bioacrylic by more than  85 percent in its pilot production process, using sugars and syngas as  feedstocks.</p>
<p><strong>Product of the Year</strong> (bio-based products) went to <strong>Genencor</strong> for its development of bioisoprene and, in partnership with Goodyear,  the development of renewable technology for the production of tires,  using a novel fermentation process based on  an engineered molecule.</p>
<p><strong>Project of the Year </strong>went to <strong>Neste Oil</strong> for the completion and start-up of its massive 240 million gallon renewable diesel plant in Singapore.</p>
<p><strong>Technology of the Year Awards</strong> went to <strong>LanzaTech</strong>, the partnership of <strong>Rentech</strong> and <strong>ClearFuels Technology</strong>, the partnership of <strong>Taurus Energy </strong>and <strong>SEKAB</strong>, and <strong>Renewable Energy Group</strong>. These awards recognized pre-pilot, pilot, demonstration-scale and commercial-scale installations.</p>
<p>LanzaTech is commercializing the fermentation of waste steel gases  into ethanol and other bio-based chemicals, with a pilot in New Zealand  and a forthcoming demonstration of its technology in China. Rentech and  ClearFuels have combined on a gasification and Fisher-Tropsch processing  of biomass into synthetic jet or diesel fuels, in a project that will  be built at Rentech’s Product demonstration Unit in Colorado, and has  been supported by a $23 million grant from the US Department of Energy.   Taurus Energy and SEKAB have combined on a cellulosic ethanol process,  using Taurus Energy’s yeast strains and SEKAB’s demonstration-scale  cellulosic ethanol plant in Sweden. Renewable Energy Group was honored  for its novel continuous-flow, multi-feedstock processing technology  that has allowed the company to pioneer the acquisition of a wide  variety of hard-to-process, low-cost feedstocks such as tallows and  yellow grease.</p>
<p>The town of <strong>Emmetsburg, Iowa</strong> was recognized as <strong>Community of the Year</strong> for the transformation of the small local community’s economy through  corn and cellulosic ethanol. The town is the site of POET’s Project  LIBERTY, a 20 million gallon cellulosic ethanol demonstration, bolted  onto an existing corn ethanol plant, which also is home to advanced work  by <strong>POET BIOMASS</strong> in corb cob and agricultural residue harvest and logistics.</p>
<p>For Project Structure, Biofuels Digest recognized <strong>ZeaChem</strong>, for creativity in financial structure, as well as <strong>BlueFire Renewables</strong>, for off-take and feedstock contracting. <strong>Sapphire Energy</strong> received the “Plan for Scale” award for its design of its  algal  biofuels system with planned demonstration scale facility in 2014 and  first commercial facility in 2018.</p>
<p>The Digest recognizes <strong>Iowa State University</strong> as Institutional Research Facility of the Year, the <strong>Joint BioEnergy Institute</strong> as Government-Institutional Research Facility of the Year, and the <strong>Energy Biosciences Institute</strong> as Public-private Research facility of the Year. JBEI’s researchers  have been notably active in the development of novel technologies  utilized by, among others, Amyris and LS9, while EBI has lately funded  research that resulted in a newly engineered yeast strain, that can  simultaneously consume glucose, a six-carbon sugar that is relatively  easy to ferment; and xylose, a five-carbon sugar that has been much more  difficult to utilize in ethanol production. Iowa State’s BioCentury  Research Farm provides researchers with the opportunity to integrate  harvesting, transportation, storage, and processing, as well as test  plant breeding, genomics, cropping systems, soil conservation and  nutrient management.</p>
<p>Partnerships were recognized in several awards this year. The <strong>Corporate partnership</strong> of <strong>Boeing</strong>, <strong>Air China</strong> and <strong>PetroChina</strong> is recognized for pioneering the testing and availability of  jatropha-based aviation biofuels for the key China aviation market. <strong>Algenol</strong> and <strong>Lee County</strong> (Florida) were recognized for Public private partnership (county) of  the Year, a partnership which has resulted in a state-of-the-art algal  biofuels research center in southwest Florida as well as a future  pilot-scale algal farm. <strong>Enerkem</strong> and the <strong>US state of Mississippi</strong> were recognized for Public private partnership (state or province) of  the Year for their work in developing the Pontotoc, MS cellulosic  ethanol project using municipal solid waste. <strong>Ineos BIO</strong> and the <strong>US Department of Energy</strong> are recognized as Public private partnership (National) of the Year for  their cooperation in bringing the Vero Beach, Florida cellulosic  ethanol demonstration plant to fruition on schedule. The <strong>US Department of Agriculture</strong> and the <strong>US Navy</strong> are recognized for Public-public partnership of the Year for their  cooperative work in developing advanced biofuels for naval onshore and  fleet operations. Finally, <strong>Cosan</strong> and <strong>Shell</strong> are recognized as Joint Venture of the Year for their $14 billion  combination of ethanol, advanced biofuels, sugarcane and fuel  distribution assets in Brazil.</p>
<p>In Feedstock development, <strong>Ceres</strong> is recognized as  Feedstock research project of the year (new feedstock or traits) for its  development of seawater-tolerant energy grasses. <strong>SG Biofuels </strong>is  recognized as Feedstock domestication project of the Year (new  feedstock or traits) for its development of the JMax platform for  jatropha in Cehtral America. <strong>Genera Energy</strong> is  recognized as Feedstock grower development project of the year for its  work in developing a switchgrass-grower network in Tennessee.</p>
<p>The <strong>Bio-XCell</strong> project in Iskandar, Malaysia is  recognized as Multi-project (co-location, or symbiosis) development of  the Year, for its custom-built biotechnology park and ecosystem being  developed by Malaysian Biotechnology Corporation and UEM Land Holdings,  which will become home to the GlycosBio demonstration-scale project  among other tenants in 2012.</p>
<p><strong>Statoil</strong> was recognized as Downstream partner of the  Year for its work with Inbicon, Bioarchitecture Lab and other partners  in creating investment and distribution for advanced biofuels.</p>
<p><strong>Bunge</strong> was recognized as Strategic Investor of the  Year for its investments in Solazyme, Renewable Energy Group, and its  strategic alliances with Verenium, and SG Biofuels.</p>
<p>Company of the Year SOLAZYME</p>
<p>Technology of the Year (pre pilot) RENTECH, CLEARFUELS</p>
<p>Technology of the Year (pilot) LANZATECH</p>
<p>Technology of the Year (demonstration state) TAURUS ENERGY, SEKAB</p>
<p>Technology of the Year (commercial stage) RENEWABLE ENERGY GROUP</p>
<p>Product of the Year (fuel) AMYRIS – FARNESENE</p>
<p>Product of the Year (renewable chemicals) GENENCOR – BIOISOPRENE</p>
<p>Product of the Year (bio-based products) OPX BIOTECHNOLOGY – BIOACRYLIC</p>
<p>Project of the Year NESTE OIL, SINGAPORE</p>
<p>Project Structure of the Year (off-take and feedstock contracting) BLUEFIRE RENEWABLES</p>
<p>Project Structure of the Year (creativity in financing) ZEACHEM</p>
<p>Community of the Year EMMETSBURG, IOWA</p>
<p>Institutional Research Facility of the Year IOWA STATE UNIVERSITY</p>
<p>Government Research Facility of the Year JOINT BIOENERGY INSTITUTE</p>
<p>Public-private Research Facility of the Year ENERGY BIOSCIENCES INSTITUTE</p>
<p>Corporate partnership of the Year BOEING, AIR CHINA, PETROCHINA</p>
<p>Public private partnership (county) of the Year ALGENOL – Lee County, FL</p>
<p>Public private partnership (state) of the Year ENERKEM</p>
<p>Public private partnership (federal) of the Year Ineos BIO, US Department of Energy</p>
<p>Public-public partnership of the Year US Department of Agriculture, US NAVY</p>
<p>Joint venture of the Year COSAN, SHELL</p>
<p>Plan for Scale SAPPHIRE ENERGY</p>
<p>Feedstock research project of the year (new feedstock or traits) CERES</p>
<p>Feedstock domestication project of the Year (new feedstock or traits) SG BIOFUELS</p>
<p>Feedstock grower development project of the year GENERA ENERGY</p>
<p>Multi-project (co-location, or symbiosis) development of the Year BIO-XCELL – ISKANDAR, MALAYSIA</p>
<p>Downstream partnership of the Year STATOIL</p>
<p>Top Strategic Investor BUNGE</p>
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		<title>Palm oil outlook positive in Asia</title>
		<link>http://www.glycosbio.com/palm-oil-outlook-positive-in-asia/</link>
		<comments>http://www.glycosbio.com/palm-oil-outlook-positive-in-asia/#comments</comments>
		<pubDate>Mon, 06 Dec 2010 17:49:55 +0000</pubDate>
		<dc:creator>client</dc:creator>
				<category><![CDATA[News]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=907</guid>
		<description><![CDATA[Biotech companies Glycos Biotechnologies of the US and Malaysia's Bio-XCell have also entered a joint venture to build a biochemical and biotechnology centre in Malaysia that would utilise glycerine to produce bio-chemicals. The centre will be completed in 2012. ]]></description>
			<content:encoded><![CDATA[<p><strong><em>By Dr. N. Yogaratnam</em></strong></p>
<p>The vegetable oil industry has witnessed significant growth over the  past few years on account of a growing population as well as the rising  demand for alternative energy sources. Among the various types of  vegetable oil, palm oil (including palm kernel) accounted for the  largest share of the global production in 2009, followed by soybean and  rapeseed oil.</p>
<p>Of the available vegetable oils, palm oil is the most productive and  has the lowest cost of production, thus accounting for the major share  of the global vegetable oil output. In recent years, the rising health  concerns have also accelerated the demand for palm oil, particularly in  developed markets.</p>
<p>Palm oil use is broadly separated into food and non-food categories.  The product is mainly used as cooking oil but is also increasingly being  used in the preparation of other food articles. As a non-food  ingredient, the product finds application in the production of  cosmetics, toiletries, soaps and detergents.</p>
<p>Although, FMCG is the largest market, the utilisation of palm oil for  the production of bio-diesel has been growing steadily. Apart from this,  the switch of consumers from loose oil to packed oil, particularly in  emerging markets, is also expected to boost the palm oil industry&#8217;s  growth in the future.</p>
<p>Geographically, Indonesia and Malaysia are the largest producers of  palm oil, while China and the EU are the largest consumers. In Europe,  Germany is the largest consumer of palm oil, followed by France and  Italy. The emerging markets, like China, India and Indonesia consume  more than 80% of palm oil. Due to rising population and increasing  income, the emerging markets including China and India are anticipated  to record an increase in demand for palm oil.</p>
<p>After bouncing back from the recession, Malaysian and Indonesian palm  oil demand is set to rise strongly, with new uses driving growth<br />
Oleo-chemical industry<br />
The oleo-chemical industry in Southeast Asia is expected to enjoy  robust growth in 2010-2012, fuelled by a short-term hike in demand from  consumer markets and wider availability of raw materials such as palm  oil, palm kernel oil and coconut oil.</p>
<p>Long-term growth is expected to be stimulated by growing markets for green chemicals and uses in new applications.</p>
<p>On the other hand, the Asian oleo-chemical industry faces the  challenges posed by the slowdown in global demand in export markets  following the October 2008 economic crisis and increasing competition  from cash-rich plantations and petrochemical companies that are keen to  get a slice of the oleo-chemical production pie.</p>
<p>In Southeast Asia, oleo-chemical production is mainly centred on the  manufacture of fatty acids, fatty alcohols, methyl esters and refined  glycerine.</p>
<p>These then go into the end-use applications of surfactants, soap and  detergents, cosmetics and food emulsifiers. New applications driving  growth are in the areas of bio-lubricants, green chemicals, bio-plastics  and biopolymers.</p>
<p>Although export markets and the global oleo-chemical industry  experienced a slowdown in 2009 in the aftermath of the crisis of October  2008, the first half of 2010 saw an improvement in demand for  Asian-based oleo-chemicals.</p>
<p>Industry outlook<br />
Fatty acid demand is expected to continue to be strong in 2010, fuelled  by growth in consumer products such as cosmetics and plastics. Prices  of fatty acids in Asia are dependent on feedstock palm kernel, palm  stearin and crude palm oil prices and tend to follow the price trends of  these raw materials.</p>
<p>The first half of 2010 saw prices of most fatty acid groups rising  month-on-month, in tandem with higher feedstock values. In the second  half of the year, prices of most fatty acids are also expected to remain  firm as a result of higher projected feedstock values.</p>
<p>The total capacity output of fatty acids in Southeast Asia is estimated  to be 3.5m tonnes in 2010, with oleo-chemical production in Malaysia  alone accounting for around 57% of that worldwide.</p>
<p>Similarly, fatty alcohol production is expected to grow at a rate of 5%  in 2010 as demand for consumer products such as detergents and  industrial surfactants is expected to increase year on year.</p>
<p>Prices have steadily increased for both mid-cut and long-chain alcohols  since January and reached a historical high for mid-cut alcohols in  August at levels above $2,000/tonne (€1,531/tonne) FOB (free on board)  Southeast Asia.</p>
<p>Prices in the second half of the year are expected to continue to rise  on the back of tight supply amid a few regional plant shutdowns, as well  as higher feedstock values.</p>
<p>New uses for refined glycerine<br />
In the refined glycerine space, growth is expected to be slower in 2010  but is predicted to pick up in 2011-2012, fuelled by newer applications  such as those of epichlorohydrin (ECH), propylene glycol (PG) and other  new applications currently under research, including aromatic solvents  and polymers.</p>
<p>2010 has also seen weaker demand for refined glycerine as a result of oversupply in the market.</p>
<p>The projected growth of the refined glycerine industry is around 5.8%  in 2010. The estimated demand for refined glycerine in 2010 is expected  to be around 280,000 tonnes, while it is estimated that supply from  oleo-chemical production including China, will be double demand, at  543,000 tonnes.</p>
<p>Prices in the second half of the year are expected to remain  soft-to-stable as the weak demand situation is likely to persist until  the end of the year.</p>
<p>Integration appreciation<br />
The government initiatives include development of palm oil industrial  clusters into integrated sites for promoting downstream activities such  as bio-fuels, oleo-chemicals, bio-fertilisers, specialty food and  biomass products, nutraceuticals and pharmaceuticals. These initiatives  are expected to boost the country&#8217;s reputation as a global leader in the  value-added space of palm oil products.</p>
<p>With 16 oleo-chemical plants with a combined capacity of 1.9m  tonnes/year, there is much potential for growth in the global  oleo-chemical space in Malaysia.</p>
<p>Future capacity expansion<br />
The growth in the oleo-chemical industry is expected to remain strong,  especially in Malaysia. New capacity is expected to be added. This  includes an expansion plan by Malaysia&#8217;s Emery Oleochemical to boost its  fatty acid capacity from 600,000 tonnes to 900,000 tonnes by 2012.</p>
<p>Biotech companies Glycos Biotechnologies of the US and Malaysia&#8217;s  Bio-XCell have also entered a joint venture to build a biochemical and  biotechnology centre in Malaysia that would utilise glycerine to produce  bio-chemicals. The centre will be completed in 2012.</p>
<p>In Indonesia, Singapore agriculture group Wilmar International has also  entered a joint venture with US vegetable oil derivatives specialist  Elevance Renewable Sciences to set up a 180,000 tonne/year bio-refinery  at Surabaya, Indonesia, due to be operational in 2011. The bio-refinery  will produce a high-quality mix of oleo-chemicals, among other products.</p>
<p>These initiatives are expected to boost the Malaysia&#8217;s reputation as a global leader<br />
Sri Lankan scenario<br />
Sri Lanka&#8217;s interest in this sub-sector centres on the cultivation of  about 75,000 ha by five Regional Plantation Companies (RPCs), around  70,000 ha of which are in Indonesia and Malaysia, and about 5,000 ha in  Sri Lanka.</p>
<p>The revival of NR market boom, although known to be very volatile, may  dampen the enthusiasm generated among some plantation companies. Yet, as  the oil palm forecasts look very stimulating and attractive in the long  term, crop diversification strategies planned and adopted by some RPCs  are expected to grow.</p>
<p>The Ministry of Plantation Industries also proposes to expand the land  extent under oil palm from the current 5,000 hectares to 25,000 hectares  as a tree crop diversification policy for sustainable development of  this sector. A public-private sector partnership becomes crucial in this  programme.</p>
<p>Research and innovation<br />
The palm oil industry needs to increase yield through research and  innovation. It is a fact that oil palm has the highest yield per hectare  and also has the highest productivity cycle of 25 years. But one can  grow the oil palms only in the equator, which means any more land  clearing would have a catastrophic impact on the world&#8217;s climate.  Therefore, it has become important to increase productivity and quality  through research and innovation.</p>
<p>There is a need to implement process improvements such as  mechanisation, automation, yield forecasting, fertiliser programmes,  focal feeding, etc.</p>
<p>In 2010, palm oil is expected to account for 34 per cent or 44 million  metric tonnes (MT) of the global vegetable oil supply and yet, it  occupies less than five per cent of total agricultural space. With the  global population projected at 7.2 billion by 2015, this trend is  expected to reverse itself, as we expect to see palm oil commanding a 40  per cent market share at 64.5 million MT, closely followed by Soybean  oil  at 33 per cent or 53.4 million MT.</p>
<p>It has been forecasted that by 2020, palm oil should have a 46 per cent  market share at 94.3 million MT. Soybean oil will still be in the  second position by then, at 29 per cent of the market share or 60.7  million MT.</p>
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		<title>Cellulosic producers advance projects</title>
		<link>http://www.glycosbio.com/cellulosic-producers-advance-projects/</link>
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		<pubDate>Mon, 08 Nov 2010 19:21:50 +0000</pubDate>
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				<category><![CDATA[News]]></category>

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		<description><![CDATA[Recent activities in the cellulosic ethanol industry have shown that while financing continues to be a major hurdle, technological advancements continue to be made and companies are beginning to construct their first commercial-scale facilities. ]]></description>
			<content:encoded><![CDATA[<p>By Kris Bevill</p>
<p>Recent activities in the cellulosic ethanol industry have shown that  while financing continues to be a major hurdle, technological  advancements continue to be made and companies are beginning to  construct their first commercial-scale facilities.</p>
<p><strong>BlueFire Renewables Inc.</strong><br />
BlueFire has secured 15-year offtake and feedstock supply contracts  for its proposed Fulton, Miss., plant and named Fargo., N.D.-based  Wanzek Construction Inc. as its engineering, procurement and  construction (EPC) contractor. Company CEO Arnold Klann said the  agreements will help BlueFire secure its pending $215 loan guarantee  from the U.S. DOE. “There’s no reason for this project not to get  financed, save for the governmental loans not getting through due to  bureaucratic hold-ups,” he said. “We have met and greatly exceeded every  criteria that we know of that has been set by the DOE loan guarantee  program.”</p>
<p>BlueFire’s proposed 19 MMgy facility will convert various wood waste  feedstocks into ethanol using the company’s acid hydrolysis technology.  Mobile, Ala.-based Cooper Marine &amp; Timberlands will supply the  facility with 770 dry tons per day of feedstock beginning in December  2012 at a cost of $25 per ton, according to Klann. When ethanol  production begins, Tenaska Biofuels LLC has agreed to purchase and  market all of the fuel produced at the plant. BlueFire’s sale price will  be based on a pricing contract that includes rack ethanol prices for  the area to which the fuel will be delivered, minus transportation  costs, with a kicker for renewable identification number (RIN) credits,  he said.</p>
<p><strong>Fiberight LLC</strong><br />
Fiberight and U.K.-based TMO Renewables Ltd. have agreed to design  and build 15 commercial-scale cellulosic ethanol production facilities  across the U.S. within the next five years. With capacities from 10 to  15 MMgy, they will utilize a combination of TMO’s process technology and  Fiberight’s fractionation and digestion technology to convert municipal  solid waste (MSW) to ethanol at a more efficient, cost-effective pace.   “Together, the companies are on track to become one of the largest  producers of cellulosic ethanol in the U.S. during 2011, helping to  divert millions of tons of waste away from landfills every year,” said  Fiberight CEO Craig Stuart-Paul. Fiberight’s 5 MMgy facility in  Blairstown, Iowa, will serve as the initial site and others in the  Mid-Atlantic and Florida areas have been identified for the next five  plants.</p>
<p><strong>Glycos Biotechnologies Inc.</strong><br />
Houston-based GlycosBio has engineered the first microbial platform  for the synthesis of biofuels and biochemicals—ethanol, butanol,  acetate, acetone, isopropanol, succinate and propionate—from fatty  acids. “Until now, microbial platforms to enable the biological  production of fuels and chemicals from fatty acids have been nearly  non-existent,” said Paul Campbell, chief science officer for GlycosBio.  “Through our research, we were able to prove the effectiveness of fatty  acids to produce higher value chemicals at very high yields with an  empirical ethanol yield double that which is usually achieved with  sugars. These results demonstrate that fatty acids can be a great  alternative to cellulosic sugars.”</p>
<p><strong>Fulcrum BioEnergy Inc.</strong><br />
CEO Jim Macias said MSW currently being tipped at landfills in the  Reno-Lake Tahoe, Nev., basin will provide approximately 90,000 tons of  annual feedstock for Fulcrum’s planned 10.5 MMgy Sierra Biofuels Plant  near Reno.</p>
<p>The company began EPC activities earlier this year and expects to  begin producing ethanol using a thermochemical process in mid-2012. A  subsidiary of Fluor Corp. was awarded the contract to provide EPC  services for the $120 million project.</p>
<p>“It took us longer to raise the capital in this very tough market,  but we’re very pleased to get this project going and demonstrate the  commercial viability, not just for our project but for the industry,”  Macias said. Fulcrum is planning projects in Houston, Colorado, Florida,  Oklahoma, Tennessee and New England.</p>
<p><strong>Enerkem Inc.</strong><br />
Enerkem broke ground Aug. 31 on its 10 MMgy MSW-to-ethanol facility  in Edmonton, Alberta, which will convert 100,000 metric tons of trash  annually when it becomes operational. “As a result of this facility, we  will become the first major city in North America to see 90 percent of  residential waste diverted from landfill by 2013,” said Edmonton Mayor  Stephen Mandel.</p>
<p>“This groundbreaking marks the launch of a transformative project  and leads the first wave of commercial-scale advanced biofuels plants in  North America,” Vincent Chornet, Enerkem president and CEO, said.  Enerkem also is developing a 20 MMgy MSW-to-ethanol project in Pontotoc,  Miss.</p>
<p><strong>American Process Inc.</strong><br />
Georgia-based API began work in August on its 900,000 gallon per  year cellulosic ethanol facility in Alpena, Mich. The plant will be  co-located with a decorative panels industrial hardwood plant and will  convert industrial wood hydrolyzate waste to ethanol and aqueous  potassium acetate beginning next year. Valero Energy Corp. is invested  in the project, which has so far also received approximately $23 million  in state and federal grants.</p>
<p><strong>Mascoma Corp.</strong><br />
Mascoma has acquired Canada’s SunOpta BioProcess Inc. for $51  million. It will use SunOpta’s first-step pretreatment process with its  own technology to produce cellulosic ethanol more efficiently and  cost-effectively. Mascoma CEO Bill Brady said the company chose  SunOpta’s technology because it is a steam explosion technology that  uses no harsh chemicals or acids. Construction is to begin at the  company’s 20 to 40 MMgy plant in Kinross, Mich., by mid-2011 and be  completed in 2013.</p>
<p><strong>KL Energy Corp.</strong><br />
Wyoming-based KL Energy is working with Brazil’s Petrobras to  develop and commercialize bagasse-to-ethanol technology. Petrobras is  investing $11 million in the project, which will be used to modify KL  Energy’s demonstration facility and fund process optimization and  technology licensing. The companies will install the technology at one  of Petrobras Group’s Brazilian sugarcane mills. The 4 MMgy project is  expected to be completed in 2013.</p>
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		<title>Glycos sets up shop in Malaysia, producing isoprene for rubber industry</title>
		<link>http://www.glycosbio.com/glycos-sets-up-shop-in-malaysia-producing-isoprene-for-rubber-industry/</link>
		<comments>http://www.glycosbio.com/glycos-sets-up-shop-in-malaysia-producing-isoprene-for-rubber-industry/#comments</comments>
		<pubDate>Fri, 05 Nov 2010 19:16:06 +0000</pubDate>
		<dc:creator>client</dc:creator>
				<category><![CDATA[News]]></category>

		<guid isPermaLink="false">http://www.glycosbio.com/?p=899</guid>
		<description><![CDATA[In Texas, Glycos Biotechnologies announced it has exchanged definitive agreements with Malaysian Bio-XCell for the establishment of the Company’s industrial biochemical plant and biotechnology R&#038;D facility in Malaysia.  The Ceremony was held in conjunction with the BioMalaysia 2010 Exhibition and Conference taking place November 1st – 3rd in Kuala Lumpur, Malaysia.]]></description>
			<content:encoded><![CDATA[<p>In Texas, Glycos Biotechnologies announced it has exchanged  definitive agreements with Malaysian Bio-XCell for the establishment of  the Company’s industrial biochemical plant and biotechnology R&amp;D  facility in Malaysia.  The Ceremony was held in conjunction with the  BioMalaysia 2010 Exhibition and Conference taking place November 1st –  3rd in Kuala Lumpur, Malaysia.</p>
<p>The company plans to focus much of its initial research and  development efforts on creating isoprene to support Malaysia’s rubber  industry.  “For Malaysia, isoprene is a strategic product because of the  large domestic latex industry and where we plan to focus much of our  R&amp;D efforts,” said Richard Cilento, Chief Executive Officer of  Glycos Biotechnologies.  “With construction underway, our long-term  strategy includes further expansion in Malaysian and across Southeast  Asia forming joint venture partnerships with existing petrochemical,  oleochemical, and biofuel producers and to partner with end market  players in the development of advanced biochemicals.</p>
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